Jefferson neighborhood in Cleveland, Ohio, currently exhibits a Moderate Diversity profile with a White Plurality. As of 2022, the white population constitutes 58% of the community, followed by Hispanic (21%) and Black (12%) populations. The neighborhood has experienced moderate population growth over the past decade, with a current population of 17,642 and a median income of $42,049. Jefferson is known for its Eastern European heritage, particularly Ukrainian and Polish influences, which contribute to its cultural landscape.

Over the past decade, Jefferson has undergone a transition in its racial composition. In 2013, the neighborhood had a White Majority, with 58% of the population identifying as white. By 2022, while the white population percentage remained stable, the community transitioned to a White Plurality due to the growth of other racial groups. The Hispanic population increased from 17% in 2013 to 21% in 2022, suggesting a trend towards a Transitional Community. The Black population decreased from 15% in 2013 to 12% in 2022, while the Asian population remained relatively stable at 2-5% throughout the decade. The "Two or More Races" category increased from 4% in 2013 to 6% in 2021, before decreasing to 4% in 2022.

The neighborhood has experienced moderate economic growth over the past decade. The median income has risen from $35,415 in 2013 to $42,049 in 2022, representing an increase of about 18.7%. This growth has not been consistent, with fluctuations observed over the years. The years of highest population growth (2017-2020) coincided with a period of relatively stable median income. The most substantial income growth occurred between 2019 and 2021, with the median income rising from $40,781 to $45,784, a 12.3% increase in two years.