The 45th and Moncrief neighborhood in Jacksonville, Florida, is classified as a "Low Diversity" community with a "Black Majority." As of 2022, the African American population constitutes 84% of residents, exceeding the 75% threshold for low diversity classification. The neighborhood has experienced modest economic growth, with the median income increasing from $21,969 in 2018 to $27,416 in 2022. This area has historical significance in Jacksonville's African American community, with roots dating back to the early 20th century when it developed as a predominantly Black neighborhood during segregation.

Over the past decade, the 45th and Moncrief neighborhood has maintained its status as a "Black Majority" area. The African American population remained dominant from 2013 to 2022, decreasing slightly from 93% to 84%. The Hispanic population increased from 1% in 2013 to 7% in 2022, indicating a trend towards a "Transitional Community." The white population remained relatively constant at 5-6% throughout the decade. The "Two or More Races" category emerged in the data from 2020 onwards, reaching 2-3% of the population.

The neighborhood's economic landscape has shown fluctuations correlating with demographic shifts. Median income decreased from $24,659 in 2013 to $21,969 in 2018, coinciding with the period of highest Black population percentage (91-95%). From 2018 to 2022, median income increased by about 25%, rising to $27,416. This improvement correlates with the slight decrease in the Black majority and the increase in Hispanic and multiracial populations. The overall population remained relatively stable, ranging from about 3,300 to 4,100 residents throughout the decade.