Otay Mesa, a neighborhood in San Diego, California, exhibits a Hispanic Majority demographic profile with 60% of its population identifying as Hispanic in 2022. The community has experienced economic growth over the past decade, with median income rising from $82,385 in 2013 to $111,537 in 2022. Otay Mesa is located on the U.S.-Mexico border, hosting a busy commercial land port of entry.

Throughout the period from 2013 to 2022, Otay Mesa has maintained its status as a Hispanic Majority community. The Hispanic population has remained between 55% and 62%. There has been a slight increase in diversity, with the Asian population growing from 5% to 6% and the Black population increasing from 17% to 18%. The White population has decreased from 15% to 14%. These changes suggest a gradual trend towards increased diversity within the Hispanic Majority framework.

The economic trajectory of Otay Mesa has been positive over the past decade. Median income has increased by 35.4% from 2013 to 2022. This income growth coincides with slight fluctuations in racial composition. The population has grown from 6,188 in 2013 to 6,402 in 2022. The rising incomes could be attributed to the neighborhood's location for international trade and commerce, potentially creating high-paying jobs in related industries.